This is a list of top 50 Men's Division I college basketball teams ranked by the number of wins though the end of the 2010–11 season.
| Rank | College | Wins | Losses | Winning percent |
|---|---|---|---|---|
| 1 | Kentucky | 2052 | 647 | .760 |
| 2 | North Carolina | 2041 | 731 | .736 |
| 3 | Kansas | 2038 | 799 | .718 |
| 4 | Duke | 1944 | 827 | .702 |
| 5 | Syracuse | 1810 | 819 | .688 |
| 6 | Temple | 1766 | 974 | .645 |
| 7 | St. John's | 1724 | 896 | .658 |
| 8 | UCLA | 1709 | 755 | .694 |
| 9 | Notre Dame | 1701 | 927 | .647 |
| 10 | Pennsylvania | 1677 | 986 | .630 |
| 11 | Utah | 1664 | 893 | .651 |
| 12 | Indiana | 1663 | 950 | .636 |
| 13 | Illinois | 1650 | 882 | .652 |
| 14 | Washington | 1641 | 1068 | .606 |
| 15 | Brigham Young | 1640 | 1005 | .620 |
| 16 | Western Kentucky | 1639 | 809 | .670 |
| 17 | Purdue | 1638 | 931 | .638 |
| 18 | Texas | 1638 | 963 | .630 |
| 19 | Louisville | 1632 | 854 | .656 |
| 20 | Oregon State | 1619 | 1218 | .571 |
| 21 | West Virginia | 1602 | 991 | .618 |
| 22 | Princeton | 1599 | 1002 | .615 |
| 23 | Cincinnati | 1598 | 940 | .630 |
| 24 | Arizona | 1595 | 880 | .644 |
| 25 | North Carolina State | 1569 | 956 | .621 |
| 26 | Bradley | 1565 | 1041 | .601 |
| 27 | Villanova | 1551 | 870 | .641 |
| 28 | Connecticut | 1549 | 864 | .642 |
| 29 | Missouri State | 1548 | 854 | .644 |
| 30 | Oklahoma | 1526 | 977 | .610 |
| 31 | Alabama | 1524 | 925 | .622 |
| 32 | Georgetown | 1520 | 946 | .616 |
| 33 | Arkansas | 1519 | 853 | .640 |
| 34 | Oklahoma State | 1517 | 1055 | .590 |
| 35 | St. Joseph's | 1499 | 1008 | .598 |
| 35 | Missouri | 1499 | 1039 | .591 |
| 37 | Ohio State | 1498 | 993 | .601 |
| 38 | Michigan State | 1496 | 1019 | .595 |
| 39 | Washington State | 1495 | 952 | .611 |
| 40 | Tennessee | 1489 | 944 | .612 |
| 41 | Iowa | 1487 | 1048 | .587 |
| 42 | Kansas State | 1486 | 1058 | .584 |
| 43 | Illinois State | 1474 | 1066 | .580 |
| 44 | USC | 1473 | 1070 | .579 |
| 45 | Dayton | 1471 | 1026 | .589 |
| 46 | Montana State | 1470 | 1179 | .555 |
| 46 | Vanderbilt | 1470 | 1035 | .587 |
| 48 | Marquette | 1467 | 905 | .618 |
| 49 | Pittsburgh | 1465 | 1048 | .583 |
| 50 | Minnesota | 1463 | 1112 | .568 |